モルヒネの禁忌まとめ

Contraindications Note: Some contraindications are product specific. For details,
please see detailed product prescribing information.

Hypersensitivity to morphine sulfate or any component of the formulation;

severe respiratory depression (without resuscitative equipment);

acute or severe asthma;

known or suspected paralytic ileus;

sustained release products are not recommended with gastrointestinal obstruction or in acute/postoperative pain.

Oral solutions contraindicated in patients with heart failure due to chronic lung disease, cardiac arrhythmias, head injuries, brain tumors, acute alcoholism, deliriums tremens, seizure disorders,

Injectable solution contraindicated during labor when a premature birth is anticipated. Some products contraindicated in patients with head injuries or increased intracranial pressure. DepoDur® contraindicated in circulatory shock and upper airway obstruction. MS Contin® and Kadian® contraindicated in patients with hypercarbia.

Some immediate release formulations (tablets and solution) contraindicated in post biliary tract surgery, suspected surgical abdomen, surgical anastomosis, MAO inhibitor use (concurrent or within 14 days), general CNS depression.